产品货号：
Z30878
中文名称：
Insig1抗体
英文名称：
Anti-Insig1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Insig1 Antibody |
| 指标别名 | insulin induced gene 1;CL6;Insig1 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,FCM |
| 基因名称 | Insig1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of rat Insig1 (MPRLHDHVWSYPSA). |
| 实际分子量 | 30KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Insulin induced gene 1,also known as INSIG1,is a protein which in humans is encoded by the INSIG1 gene.This gene encodes an endoplasmic reticulum membrane protein that regulates cholesterol metabolism,lipogenesis,and glucose homeostasis.The encoded protein has six transmembrane helices which contain an effector protein binding site.It binds the sterol-sensing domains of sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) and 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase),and is essential for the sterol-mediated trafficking of these two proteins.It promotes the endoplasmic reticulum retention of SCAP and the ubiquitin-mediated degradation of HMG-CoA reductase.Alternative splicing results in multiple transcript variants. |
| Uniprot ID | Q08755 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | insulin induced gene 1 |
| 蛋白名全称 | Insulin-induced gene 1 protein |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells |
相关搜索：Insig1抗体，Insig1多抗，Anti-Insig1 Antibody